Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.74 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.74 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.48 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | UNG | P13051 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzaldehyde SCHEMBL27520789 | 0.92 | ALDH1A1 (0.78) | ALDH1A1CYP2A6ALDH3A1ALDH1A3LMNA | |
| Benzaldehyde SCHEMBL28129001 | 0.90 | ALDH1A1 (0.67) | ALDH1A1CYP2A6ALDH3A1ALDH1A3LMNA | |
| Benzaldehyde SCHEMBL27780817 | 0.90 | ALDH1A1 (0.74) | ALDH1A1CYP2A6ALDH3A1ALDH1A3LMNA | |
| Benzaldehyde SCHEMBL28218440 | 0.88 | ALDH1A1 (0.64) | ALDH1A1CYP2A6ALDH3A1ALDH1A3LMNA | |
| Benzaldehyde SCHEMBL3860024 | 0.88 | ALDH1A1 (0.64) | ALDH1A1CYP2A6ALDH3A1ALDH1A3LMNA | |
| Benzaldehyde SCHEMBL1129906 | 0.87 | ALDH1A1 (0.70) | ALDH1A1CYP2A6ALDH3A1ALDH1A3LMNA | |
| Benzaldehyde SCHEMBL7038566 | 0.87 | ALDH1A1 (0.70) | ALDH1A1CYP2A6ALDH3A1ALDH1A3LMNA | |
| Benzaldehyde SCHEMBL28807025 | 0.87 | ALDH1A1 (0.70) | ALDH1A1CYP2A6ALDH3A1ALDH1A3LMNA | |
| Benzaldehyde SCHEMBL9780149 | 0.87 | ALDH1A1 (0.70) | ALDH1A1CYP2A6ALDH3A1ALDH1A3LMNA | |
| Benzaldehyde SCHEMBL28089327 | 0.87 | ALDH1A1 (0.70) | ALDH1A1CYP2A6ALDH3A1ALDH1A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8629268-B2 | Cyclisation process of forming a multiple ring compound | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2014-01-14 | — | — | US | disclosed |
| US-20130046090-A1 | CYCLISATION PROCESS OF FORMING A MULTIPLE RING COMPOUND | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2013-02-21 | — | — | US | disclosed |
| US-8227645-B2 | Cyclisation process of forming a multiple ring compound | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2012-07-24 | — | — | US | disclosed |
| CN-102199129-A | Method for synthetizing aromatic polyamine compounds | UNIV BEIJING CHEMICAL | 2011-09-28 | — | — | CN | disclosed |
| US-20100228058-A1 | CYCLISATION PROCESS OF FORMING A MULTIPLE RING COMPOUND | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2010-09-09 | — | — | US | disclosed |
| EP-2046896-A2 | COLOURED ORGANIC ELECTROPHORETIC PARTICLES | Ciba Holding Inc. (CH) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008003604-A2 | COLOURED ORGANIC ELECTROPHORETIC PARTICLES | CIBA HOLDING INC. (CH) | 2008-01-10 | — | — | WO | disclosed |
| WO-2007097719-A1 | CYCLISATION PROCESS OF FORMING A MULTIPLE RING COMPOUND | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2007-08-30 | — | — | WO | disclosed |
| US-4102941-A | Method for making silarylenesiloxane-polydiorganosiloxane block polymers | GENERAL ELECTRIC COMPANY (US) | 1978-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100228058-A1 | CYCLISATION PROCESS OF FORMING A MULTIPLE RING COMPOUND | DHPS, GGPS1, COASY | ALDH1A1 1419/4885CYP2A6 89/4885ALDH3A1 927/4885 |
| US-20130046090-A1 | CYCLISATION PROCESS OF FORMING A MULTIPLE RING COMPOUND | COASY, AKR1C4, AKR1C2 | ALDH1A1 438/4885CYP2A6 51/4885ALDH3A1 286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.