SCHEMBL11299136

SCHEMBL11299136

C[C@H](N)C(=O)N(C(=O)[C@H](C)N)[C@@H](C)P(=O)(O)O

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LAP3 P28838 4/20 0.41
ANPEP P15144 6/20 0.37
ERAP1 Q9NZ08 1/20 0.37
ALDH1A1 P00352 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
METAP1 P53582 1/20 0.33
ERAP2 Q6P179 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11304670 1.00 LAP3 (0.41) LAP3ANPEPERAP1ALDH1A1TDP1
SCHEMBL1582884 0.90 LAP3 (0.43) LAP3ANPEPERAP1
SCHEMBL11296904 0.87 LAP3 (0.33) LAP3ANPEPERAP1ALDH1A1TDP1
SCHEMBL1582338 0.85 ALDH1A1 (0.36) LAP3ANPEPERAP1ALDH1A1TDP1
SCHEMBL11300949 0.80 BHMT (0.33) ALDH1A1TDP1METAP1
SCHEMBL11307631 0.80 ALDH1A1 (0.41) LAP3ANPEPERAP1ALDH1A1TDP1
SCHEMBL1582659 0.77 LAP3 (0.49) LAP3ANPEP
SCHEMBL1582205 0.74 SCN4A (0.36)
SCHEMBL1582150 0.71 ANPEP (0.40) LAP3ANPEPERAP1ALDH1A1TDP1
SCHEMBL851464 0.68 LAP3 (0.36) LAP3ANPEPERAP1ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4134972-A OLIGOPEPTIDES HOFFMANN-LA ROCHE INC. (US) 1979-01-16 US claimed
US-4250085-A PHOSPHONATE-CONTAINING OLIGOPEPTIDES, BACTERICIDES HOFFMANN-LA ROCHE INC. (US) 1981-02-10 US disclosed
US-4134972-A OLIGOPEPTIDES HOFFMANN-LA ROCHE INC. (US) 1979-01-16 US disclosed
US-4128542-A OF ETHYLPHOSPHONIC ACIDS, BACTERICIDES HOFFMANN-LA ROCHE INC. (US) 1978-12-05 US disclosed
US-4127649-A PEPTIDES HOFFMANN-LA ROCHE INC. (US) 1978-11-28 US disclosed
US-4100275-A PEPTIDES HOFFMANN-LA ROCHE INC. (US) 1978-07-11 US disclosed