Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAK | O14976 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11299758 | 0.68 | GAK (0.56) | GAKALDH1A1TSHRMAPK1LMNA | |
| SCHEMBL14360622 | 0.66 | MAPT (0.54) | GAKALDH1A1TSHRMAPK1LMNA | |
| SCHEMBL3754226 | 0.65 | GAK (0.67) | GAKALDH1A1MAPK1LMNAUSP2 | |
| SCHEMBL14478929 | 0.64 | MAPK1 (0.62) | ALDH1A1TSHRMAPK1LMNAUSP2 | |
| SCHEMBL7017261 | 0.64 | MAPK1 (0.49) | GAKALDH1A1TSHRMAPK1LMNA | |
| Potassium Ion SCHEMBL3689408 | 0.63 | GAK (0.63) | GAKALDH1A1TSHRMAPK1LMNA | |
| SCHEMBL1622150 | 0.63 | ABCB1 (0.56) | GAKALDH1A1TSHRMAPK1LMNA | |
| SCHEMBL19090358 | 0.62 | CYP1A2 (0.58) | ALDH1A1TSHRMAPK1LMNAHTT | |
| SCHEMBL12877215 | 0.62 | LMNA (0.79) | ALDH1A1MAPK1LMNAUSP2HTT | |
| SCHEMBL1101894 | 0.62 | MAPK1 (0.60) | GAKALDH1A1TSHRMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56034683-A | — | — | None | — | — | JP | disclosed |
| JP-S5634683-A | DIMETHYLTHIENOPYRIMIDINONE DERIVATIVE | SHOWA DENKO KK | 1981-04-06 | — | — | JP | disclosed |