Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAK | O14976 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11301157 | 0.69 | ALDH1A1 (0.47) | GAKMAPK1ALDH1A1GAAHPGD | |
| SCHEMBL11299230 | 0.68 | GAK (0.57) | GAKMAPK1ALDH1A1GAAHPGD | |
| SCHEMBL11518343 | 0.61 | KDM4E (0.71) | MAPK1ALDH1A1GAAHPGDKDM4E | |
| SCHEMBL12310881 | 0.59 | ALDH1A1 (0.46) | ALDH1A1GAAHPGDKDM4ECYP1A2 | |
| SCHEMBL7017261 | 0.59 | MAPK1 (0.49) | GAKMAPK1ALDH1A1GAAPOLB | |
| SCHEMBL11485343 | 0.58 | ELANE (0.60) | ALDH1A1GAAHPGDKDM4ECYP1A2 | |
| SCHEMBL12892166 | 0.57 | HTT (0.68) | MAPK1ALDH1A1GAAPOLBLMNA | |
| SCHEMBL5265815 | 0.57 | ALDH1A1 (0.69) | MAPK1ALDH1A1GAAHPGDKDM4E | |
| SCHEMBL12877215 | 0.57 | LMNA (0.79) | MAPK1ALDH1A1HPGDKDM4EPOLB | |
| SCHEMBL12261730 | 0.57 | GAK (0.43) | GAKMAPK1ALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56059778-A | — | — | None | — | — | JP | disclosed |
| JP-S5659778-A | DIMETHYLTHIENOPYRIMIDIONE DERIVATIVE | SHOWA DENKO KK | 1981-05-23 | — | — | JP | disclosed |