SCHEMBL11299323

SCHEMBL11299323

O=C(N(Cc1ccccc1)c1ccccc1[N+](=O)[O-])C(F)(F)F

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
LMNA P02545 1/20 0.46
KDM4E B2RXH2 1/20 0.45
PTPN1 P18031 2/20 0.43
KMT2A Q03164 3/20 0.42
MEN1 O00255 2/20 0.42
CRHBP P24387 1/20 0.42
CRHR2 Q13324 1/20 0.42
SNCA P37840 1/20 0.41
AR P10275 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
GAA P10253 1/20 0.39
RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27459943 0.83 ALDH1A1 (0.41) ALDH1A1KMT2AMEN1RAB9A
SCHEMBL14377803 0.83 SMN1; SMN2 (0.49) ALDH1A1LMNAKMT2ACRHBPCRHR2
SCHEMBL13729336 0.80 KDM4E (0.48) ALDH1A1LMNAKDM4EKMT2AMEN1
SCHEMBL13729340 0.80 KDM4E (0.48) ALDH1A1LMNAKDM4EKMT2AMEN1
SCHEMBL7319626 0.78 ALDH1A1 (0.48) ALDH1A1LMNAKDM4EKMT2AMEN1
SCHEMBL15695027 0.77 ALDH1A1 (0.47) ALDH1A1LMNAKDM4EKMT2AMEN1
SCHEMBL22499483 0.77 MEN1 (0.36) ALDH1A1KDM4EKMT2AMEN1SNCA
SCHEMBL22499480 0.77 MEN1 (0.36) ALDH1A1KDM4EKMT2AMEN1SNCA
SCHEMBL11293523 0.77 PDK1 (0.43) ALDH1A1
SCHEMBL13729331 0.75 ALDH1A1 (0.51) ALDH1A1LMNAKDM4EKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0003263-B1 A METHOD OF FORMING AN IMAGE, AND AN IMAGING ELEMENT FOR INHIBITING IMAGE FORMATION WITH COBALT (III) COMPLEXES EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1982-09-29 EP claimed
EP-0003263-A1 A method of forming an image, and an imaging element for inhibiting image formation with cobalt (III) complexes EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1979-08-08 EP claimed
WO-1979000448-A1 INHIBITING IMAGE FORMATION WITH COBALT(III)COMPLEXES EASTMAN KODAK CO (US) 1979-07-26 WO claimed