Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | TACR2 | P21452 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6238281 | 0.85 | PTGER1 (0.49) | MAOAMAOBPTGER1PTGER4PTGER3 | |
| SCHEMBL724228 | 0.84 | PTGER1 (0.55) | PTGER1PTGER4PTGER3PTGER2MTNR1A | |
| SCHEMBL722894 | 0.83 | PTGER1 (0.44) | PTGER1PTGER4PTGER3PTGER2MTNR1A | |
| Hydrochloric Acid SCHEMBL723195 | 0.83 | PTGER1 (0.54) | PTGER1PTGER4PTGER3PTGER2MTNR1A | |
| SCHEMBL7758338 | 0.82 | PTGER1 (0.46) | PTGER1PTGER4PTGER3PTGER2MTNR1A | |
| SCHEMBL11300806 | 0.81 | AKR1C3 (0.36) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL1901763 | 0.81 | PTGER1 (0.47) | PTGER1PTGER4PTGER3PTGER2SMN1; SMN2 | |
| SCHEMBL2431823 | 0.81 | CDK1 (0.35) | MAOAMAOBALDH1A1RAB9ATDP1 | |
| SCHEMBL724160 | 0.79 | HTR1A (0.39) | PTGER1PTGER4PTGER3PTGER2ALDH1A1 | |
| SCHEMBL11296369 | 0.77 | NAT1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012098560-A2 | PROCESS FOR THE PREPARATION OF MUSCARINIC RECEPTOR ANTAGONIST | MSN LABORATORIES LIMITED (IN) | 2012-07-26 | — | — | WO | disclosed |