SCHEMBL11296369

SCHEMBL11296369

C=C(Cc1ccc(C=O)cc1CCCc1cccc(N(C(C)C)C(C)C)c1)C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NAT1 P18440 1/20 0.34
LTB4R Q15722 3/20 0.31
AKR1C3 P42330 1/20 0.30
AKR1C2 P52895 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2431823 0.82 CDK1 (0.35)
SCHEMBL11300806 0.80 AKR1C3 (0.36) AKR1C3AKR1C2
SCHEMBL11299423 0.77 MAOA (0.44)
SCHEMBL6473875 0.69 GRIN2D (0.41)
SCHEMBL6238281 0.66 PTGER1 (0.49)
SCHEMBL11297469 0.66 CHRM2 (0.35) AKR1C3AKR1C2
SCHEMBL3721174 0.66 IGF1R (0.39)
SCHEMBL11304898 0.65 CHRM3 (0.45) NAT1
SCHEMBL724700 0.65 ADRB2 (0.39) LTB4R
SCHEMBL4190007 0.65 BACE1 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012098560-A2 PROCESS FOR THE PREPARATION OF MUSCARINIC RECEPTOR ANTAGONIST MSN LABORATORIES LIMITED (IN) 2012-07-26 WO claimed