Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11424839 | 0.82 | TSHR (0.39) | TSHRCYP1A2LTA4HKCNA3KIF11 | |
| SCHEMBL16782648 | 0.76 | LTA4H (0.38) | TSHRLTA4HKCNA3RIPK1ALDH1A1 | |
| SCHEMBL29071119 | 0.73 | TSHR (0.48) | TSHRCYP1A2LTA4HKCNA3KIF11 | |
| SCHEMBL9798410 | 0.73 | TSHR (0.48) | TSHRCYP1A2LTA4HKCNA3KIF11 | |
| SCHEMBL29222025 | 0.72 | ALDH1A1 (0.35) | TSHRLTA4HKCNA3MAPK1RIPK1 | |
| SCHEMBL4616313 | 0.70 | TSHR (0.45) | TSHRCYP1A2KIF11MAPK1ALDH1A1 | |
| SCHEMBL11419517 | 0.70 | TSHR (0.45) | TSHRCYP1A2KIF11MAPK1ALDH1A1 | |
| SCHEMBL16793318 | 0.70 | TSHR (0.44) | TSHRCYP1A2LTA4HKIF11MAPK1 | |
| SCHEMBL3924740 | 0.70 | LTA4H (0.36) | TSHRLTA4HKCNA3RIPK1ALDH1A1 | |
| SCHEMBL53548 | 0.69 | TSHR (0.45) | TSHRCYP1A2LTA4HKCNA3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0057600-A2 | Affinity resins and their use in isolating bacterial luciferase | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 1982-08-11 | — | — | EP | claimed |