SCHEMBL3924740

SCHEMBL3924740

[SiH3]C(CCl)(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.36
TSHR P16473 1/20 0.36
KCNA3 P22001 1/20 0.36
RIPK1 Q13546 1/20 0.33
CA4 P22748 1/20 0.33
TAAR1 Q96RJ0 1/20 0.32
ALDH1A1 P00352 1/20 0.32
RECQL P46063 1/20 0.32
ALOX15 P16050 1/20 0.31
PPARG P37231 1/20 0.31
PPARA Q07869 1/20 0.31
RNF4 P78317 1/20 0.31
CA5A P35218 1/20 0.30
CA5B Q9Y2D0 1/20 0.30
TTR P02766 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3923259 0.79 KCNA3 (0.40) LTA4HTSHRKCNA3TAAR1ALDH1A1
SCHEMBL3924731 0.77 TSHR (0.36) LTA4HTSHRKCNA3CA4TAAR1
SCHEMBL5031082 0.76 KCNA3 (0.44) LTA4HKCNA3TAAR1ALDH1A1RECQL
SCHEMBL16782648 0.74 LTA4H (0.38) LTA4HTSHRKCNA3RIPK1CA4
SCHEMBL188025 0.72 LTA4H (0.45) LTA4HTSHRKCNA3CA4TAAR1
SCHEMBL29222025 0.71 ALDH1A1 (0.35) LTA4HTSHRKCNA3RIPK1CA4
SCHEMBL3917622 0.71 KCNA3 (0.35) LTA4HTSHRKCNA3
SCHEMBL3815410 0.71 KIF11 (0.47) LTA4HTAAR1
SCHEMBL11299608 0.70 TSHR (0.41) LTA4HTSHRKCNA3RIPK1CA4
SCHEMBL6003069 0.69 LTA4H (0.41) LTA4HTSHRKCNA3CA4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7619108-B2 Process for preparing unsaturated organosilicon compounds WACKER CHEMIE AG (DE) 2009-11-17 US disclosed
EP-1954701-B1 PROCESS FOR PREPARING UNSATURATED ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2009-03-18 EP disclosed
US-20080293958-A1 Process for Preparing Unsaturated Organosilicon Compounds WACKER CHEMIE AG (DE) 2008-11-27 US disclosed
US-6815554-B2 REACTING A HALOALKYLSILANE WITH A SALT OF AN UNSATURATED CARBOXYLIC ACID IN THE PRESENCE OF A PHASE TRANSFER CATALYST; BONDING AGENTS WACKER-CHEMIE GMBH (DE) 2004-11-09 US disclosed
US-20020151736-A1 PROCESS FOR PREPARING UNSATURATED ORGANOSILICON COMPOUNDS WACKER-CHEMIE GMBH (DE) 2002-10-17 US disclosed
EP-1249454-A1 Preparation of unsaturated organo-silicon compounds Wacker-Chemie GmbH (DE) 2002-10-16 EP disclosed