Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | RORB | Q92753 | 6/20 | 0.53 |
| ▸ | RORC | P51449 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ACR | P10323 | 1/20 | 0.46 |
| ▸ | SMO | Q99835 | 1/20 | 0.46 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11301214 | 0.89 | RAB9A (0.55) | SMN1; SMN2NPC1RAB9ARORBMAPT | |
| SCHEMBL11271217 | 0.83 | LMNA (0.46) | SMN1; SMN2NPC1RAB9ARORBMAPT | |
| SCHEMBL11293488 | 0.81 | SMN1; SMN2 (0.65) | SMN1; SMN2NPC1RAB9ACYP1A2CYP2C19 | |
| SCHEMBL11291758 | 0.81 | IL2 (0.61) | SMN1; SMN2CYP1A2CYP2C19MAPTLMNA | |
| SCHEMBL11268396 | 0.81 | GAA (0.50) | SMN1; SMN2NPC1RAB9ACYP1A2CYP2C19 | |
| SCHEMBL11292823 | 0.80 | LMNA (0.46) | SMN1; SMN2NPC1RAB9ACYP1A2CYP2C19 | |
| SCHEMBL11300373 | 0.78 | RAB9A (0.56) | SMN1; SMN2NPC1RAB9AMAPTLMNA | |
| SCHEMBL3455896 | 0.76 | RXFP1 (0.88) | SMN1; SMN2RXFP1MAPTLMNAALDH1A1 | |
| SCHEMBL30643207 | 0.75 | EPAS1 (0.59) | SMN1; SMN2NPC1RAB9ACYP1A2CYP2C19 | |
| SCHEMBL31606893 | 0.75 | RXFP1 (0.62) | SMN1; SMN2RXFP1RORBRORCMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322429-A | Isoxazolylbenzamides as insecticides | ELI LILLY AND COMPANY (US) | 1982-03-30 | — | — | US | claimed |