Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ACR | P10323 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8661526 | 0.89 | RAB9A (0.50) | GAANPC1RAB9ACYP1A2CYP2C19 | |
| SCHEMBL11261749 | 0.88 | RAB9A (0.46) | GAAEPHX2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11253471 | 0.87 | NPC1 (0.52) | GAAEPHX2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11264322 | 0.85 | GAA (0.52) | GAAEPHX2NPC1RAB9AACR | |
| SCHEMBL11300373 | 0.81 | RAB9A (0.56) | EPHX2NPC1RAB9ASMN1; SMN2ACR | |
| SCHEMBL11299668 | 0.81 | SMN1; SMN2 (0.55) | NPC1RAB9ACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL11254846 | 0.81 | EPHX2 (0.46) | GAAEPHX2NPC1RAB9AACR | |
| SCHEMBL11257811 | 0.80 | TRPV1 (0.48) | GAATDP1TP53TRPV1RORC | |
| SCHEMBL11293488 | 0.79 | SMN1; SMN2 (0.65) | GAANPC1RAB9ACYP1A2CYP2C19 | |
| SCHEMBL11271217 | 0.79 | LMNA (0.46) | GAANPC1RAB9ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336264-A | 1-Benzoyl-3-(isoxazolyl or benzisoxazolyl)-ureas and insecticidal use thereof | ELI LILLY AND COMPANY (US) | 1982-06-22 | — | — | US | claimed |