Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDAH1 | O94760 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 5/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11218846 | 0.84 | AAK1 (0.53) | DDAH1ABL1GAAHTTTLR8 | |
| SCHEMBL8592534 | 0.82 | DDAH1 (0.53) | DDAH1GAAHTT | |
| SCHEMBL11275736 | 0.82 | ABL1 (0.45) | ABL1MAP4K4DYRK1ATLR8TLR7 | |
| SCHEMBL13963923 | 0.80 | DDAH1 (0.59) | DDAH1GAAHTTAAK1 | |
| SCHEMBL11261025 | 0.79 | ABL1 (0.44) | ABL1MAP4K4DYRK1ATLR8TLR7 | |
| SCHEMBL11262069 | 0.79 | DYRK1A (0.44) | ABL1MAP4K4DYRK1ATLR8TLR7 | |
| SCHEMBL12350634 | 0.79 | DDAH1 (0.62) | DDAH1GAAHTTDYRK1ACLK1 | |
| SCHEMBL11270703 | 0.78 | CYP1A2 (0.47) | ABL1HTTDYRK1A | |
| SCHEMBL10038839 | 0.75 | DDAH1 (0.59) | DDAH1GAAHTT | |
| SCHEMBL11309998 | 0.74 | POLB (0.41) | AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0056260-A1 | Pyridinyl-substituted-benz imidazole derivatives and preparation | STERLING DRUG INC. (US) | 1982-07-21 | — | — | EP | disclosed |