Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 5/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CDC25A | P30304 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11271873 | 0.89 | KDM4C (0.39) | ABL1KDM4CTLR8TLR7TLR9 | |
| SCHEMBL11271918 | 0.86 | MMP2 (0.49) | ABL1KDM4CTLR8TLR7TLR9 | |
| Water SCHEMBL11275606 | 0.84 | MMP2 (0.48) | ABL1KDM4CTLR8TLR7TLR9 | |
| SCHEMBL11271590 | 0.83 | NPC1 (0.46) | DYRK1AKDM4CMMP2MMP13MMP14 | |
| SCHEMBL11299685 | 0.82 | DDAH1 (0.47) | ABL1DYRK1AMAP4K4TLR8TLR7 | |
| SCHEMBL11263840 | 0.80 | KDM4C (0.38) | KDM4CTLR8TLR7TLR9MMP13 | |
| SCHEMBL11270413 | 0.78 | CYP11B2 (0.58) | ABL1KDM4CTLR8TLR7MMP2 | |
| SCHEMBL11262069 | 0.78 | DYRK1A (0.44) | ABL1DYRK1AMAP4K4TLR8TLR7 | |
| SCHEMBL11261025 | 0.78 | ABL1 (0.44) | ABL1DYRK1AMAP4K4TLR8TLR7 | |
| SCHEMBL20436746 | 0.77 | KDM4C (0.43) | KDM4CMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0055453-A2 | 5-(Pyridinyl)-benzimidazole derivatives and preparation | STERLING DRUG INC. (US) | 1982-07-07 | — | — | EP | disclosed |
| US-4335132-A | 5-(Py-Y)-1H-benzimidazol-2-ols and 5-(Py-Y-)-1H-benzimidazole-2-thiols | STERLING DRUG, INC. (US) | 1982-06-15 | — | — | US | disclosed |