Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11289843 | 0.91 | MAPT (0.38) | KMT2AMAPTADAM17ATMALDH1A1 | |
| SCHEMBL11279654 | 0.89 | KMT2A (0.36) | KMT2AMAPTADAM17ATMALDH1A1 | |
| SCHEMBL11292381 | 0.88 | RORC (0.39) | KMT2AMAPTADAM17ATMALDH1A1 | |
| SCHEMBL11291159 | 0.87 | CTNNB1 (0.40) | KMT2AMAPTADAM17ATMALDH1A1 | |
| SCHEMBL11292441 | 0.84 | KMT2A (0.46) | KMT2AMAPTALDH1A1L3MBTL1HPGD | |
| SCHEMBL11494781 | 0.82 | RORC (0.40) | KMT2AMAPTADAM17ATMALDH1A1 | |
| SCHEMBL11297070 | 0.81 | — | — | |
| SCHEMBL11278524 | 0.80 | MAPT (0.36) | KMT2AMAPTADAM17ATMALDH1A1 | |
| SCHEMBL11337851 | 0.79 | PTPN1 (0.33) | KMT2AMAPTATMALDH1A1L3MBTL1 | |
| SCHEMBL11290056 | 0.79 | MLYCD (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0014167-B1 | Aniline derivatives with antifungal activity and process for their preparation | RHONE-POULENC AGROCHIMIE (FR) | 1982-06-30 | — | — | EP | disclosed |
| EP-0014167-A1 | Aniline derivatives with antifungal activity and process for their preparation | RHONE-POULENC AGROCHIMIE (FR) | 1980-08-06 | — | — | EP | disclosed |