Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11289843 | 0.91 | MAPT (0.38) | CTNNB1WNT3ARORCMAPTKMT2A | |
| SCHEMBL11271249 | 0.87 | RORC (0.41) | CTNNB1WNT3ARORCMAPTKMT2A | |
| SCHEMBL11299781 | 0.87 | KMT2A (0.35) | CTNNB1WNT3ARORCMAPTKMT2A | |
| SCHEMBL11292381 | 0.87 | RORC (0.39) | CTNNB1WNT3ARORCMAPTKMT2A | |
| SCHEMBL11287633 | 0.81 | KMT2A (0.52) | MAPTKMT2AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL11278524 | 0.79 | MAPT (0.36) | CTNNB1WNT3ARORCMAPTKMT2A | |
| SCHEMBL11290774 | 0.77 | ALDH1A1 (0.36) | KMT2AALDH1A1HTTCYP3A4MEN1 | |
| SCHEMBL11298078 | 0.77 | ALDH1A1 (0.39) | MAPTALDH1A1CYP3A4LMNAOPRM1 | |
| SCHEMBL11289135 | 0.76 | OPRM1 (0.39) | MAPTKMT2AATMALDH1A1HPGD | |
| SCHEMBL11294511 | 0.76 | ALDH1A1 (0.33) | MAPTKMT2AALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0014167-B1 | Aniline derivatives with antifungal activity and process for their preparation | RHONE-POULENC AGROCHIMIE (FR) | 1982-06-30 | — | — | EP | disclosed |