Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA4 | P43681 | 3/20 | 0.37 |
| ▸ | PYGM | P11217 | 1/20 | 0.37 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11717014 | 0.85 | CHRNA4 (0.36) | CHRNA4PYGMRAPGEF3RAPGEF4ACACB | |
| SCHEMBL11722983 | 0.85 | ALDH1A1 (0.46) | CHRNA4PYGMRAPGEF3RAPGEF4ACACB | |
| SCHEMBL157610 | 0.80 | — | — | |
| SCHEMBL289997 | 0.78 | — | — | |
| SCHEMBL325207 | 0.77 | — | — | |
| SCHEMBL11720916 | 0.77 | ACACB (0.36) | CHRNA4PYGMRAPGEF3RAPGEF4ACACB | |
| SCHEMBL755315 | 0.76 | — | — | |
| SCHEMBL29348291 | 0.76 | — | — | |
| SCHEMBL11594291 | 0.76 | — | — | |
| SCHEMBL3940897 | 0.76 | CHRNA4 (0.40) | CHRNA4RAPGEF3RAPGEF4ACACBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4014876-A | HYPOGLYCEMIC | SHIONOGI & CO., LTD. (JA) | 1977-03-29 | — | — | US | claimed |
| EP-0004187-B1 | HETEROCYCLYLCARBONYL DERIVATIVES OF UREA AND THEIR USE AS AGENTS FOR DISSOLUTION OF GALLSTONES | PFIZER INC. (US) | 1982-03-17 | — | — | EP | disclosed |
| US-4163784-A | ACYLUREA DERIVATIVES | PFIZER INC. (US) | 1979-08-07 | — | — | US | disclosed |
| US-4014876-A | HYPOGLYCEMIC | SHIONOGI & CO., LTD. (JA) | 1977-03-29 | — | — | US | disclosed |