Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11299966 | 1.00 | MAOB (0.46) | MAOBTSHRMAPK10KCNH2NR4A2 | |
| SCHEMBL11303482 | 0.83 | CTBP2 (0.49) | MAOBNR4A2HCAR2MAOADHODH | |
| SCHEMBL11303480 | 0.83 | CTBP2 (0.49) | MAOBNR4A2HCAR2MAOADHODH | |
| SCHEMBL11301348 | 0.82 | TP53 (0.43) | MAOBMAPK10KDM4EGAARAB9A | |
| SCHEMBL11301345 | 0.82 | TP53 (0.43) | MAOBMAPK10KDM4EGAARAB9A | |
| SCHEMBL13799028 | 0.77 | NR4A2 (0.44) | MAOBNR4A2HCAR2SLC1A1RAB9A | |
| SCHEMBL11300920 | 0.77 | DHODH (0.43) | MAOBNR4A2MAOADHODH | |
| SCHEMBL5791660 | 0.76 | SLC1A1 (0.49) | NR4A2HCAR2SLC1A1SRC | |
| SCHEMBL11301936 | 0.75 | TSHR (0.44) | MAOBTSHRDHODHMEN1KMT2A | |
| SCHEMBL11301938 | 0.75 | TSHR (0.44) | MAOBTSHRDHODHMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4254048-A | ANTIINFLAMMATORY AGENTS; FOR ARTHRITIS | AMERICAN CYANAMID COMPANY (US) | 1981-03-03 | — | — | US | claimed |