Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | AGXT | P21549 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6864466 | 0.79 | TAAR1 (0.50) | NR4A2MAOBSLC1A1TAAR1NPC1 | |
| SCHEMBL8141233 | 0.78 | MEN1 (0.55) | NR4A2MAOBTAAR1LMNAMAPT | |
| SCHEMBL10172435 | 0.77 | GAA (0.48) | RAB9ALMNAHTTSMN1; SMN2KMT2A | |
| SCHEMBL9113 | 0.77 | AKR1B1 (0.58) | NR4A2SLC1A1TAAR1LMNAMAPT | |
| SCHEMBL13185331 | 0.77 | FOLH1 (0.37) | — | |
| SCHEMBL11299966 | 0.77 | MAOB (0.46) | NR4A2MAOBSLC1A1RAB9AMEN1 | |
| SCHEMBL11299981 | 0.77 | MAOB (0.46) | NR4A2MAOBSLC1A1RAB9AMEN1 | |
| SCHEMBL955096 | 0.77 | CES1 (0.56) | LMNAHTTMEN1KMT2AMAPK1 | |
| SCHEMBL13185333 | 0.76 | FFAR1 (0.42) | LMNAMAPK8 | |
| SCHEMBL1149255 | 0.76 | TAAR1 (0.47) | NR4A2SLC1A1TAAR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090163591-A1 | USE OF SUGAR PHOSPHATES, SUGAR PHOSPHATE ANALOGS, AMINO ACIDS AND/OR AMINO ACID ANALOGS FOR MODULATING THE GLUCOLYSIS-ENZYME COMPLEX, THE MALATE ASPARATE SHUTTLE AND/OR THE TRANSAMINASES | EIGENBRODT ERICH | 2009-06-25 | — | — | US | disclosed |
| US-20090163591-A1 | USE OF SUGAR PHOSPHATES, SUGAR PHOSPHATE ANALOGS, AMINO ACIDS AND/OR AMINO ACID ANALOGS FOR MODULATING THE GLUCOLYSIS-ENZYME COMPLEX, THE MALATE ASPARATE SHUTTLE AND/OR THE TRANSAMINASES | EIGENBRODT ERICH | 2009-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163591-A1 | USE OF SUGAR PHOSPHATES, SUGAR PHOSPHATE ANALOGS, AMINO ACIDS AND/OR AMINO ACID ANALOGS FOR MODULATING THE GLUCOLYSIS-ENZYME COMPLEX, THE MALATE ASPARATE SHUTTLE AND/OR THE TRANSAMINASES | G6PD, PDK1, PDK4 | NR4A2 3910/4885MAOB 3640/4885SLC1A1 416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.