Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | THRB | P10828 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | RORC | P51449 | 1/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11296616 | 0.88 | SMN1; SMN2 (0.54) | MAPTTHRBMAPK1RORCUSP30 | |
| SCHEMBL11296876 | 0.85 | RORC (0.63) | MAPTTHRBRORCSMN1; SMN2L3MBTL1 | |
| SCHEMBL11284045 | 0.83 | IL2 (0.57) | MAPTTHRBRORCUSP30SMN1; SMN2 | |
| SCHEMBL13901753 | 0.78 | RORC (0.73) | MAPTTHRBRORCSMN1; SMN2MEN1 | |
| SCHEMBL11293546 | 0.76 | SMN1; SMN2 (0.61) | MAPTTHRBRORCUSP30NPY5R | |
| SCHEMBL11299666 | 0.75 | USP30 (0.51) | MAPTTHRBRORCUSP30SMN1; SMN2 | |
| SCHEMBL13901755 | 0.74 | MAPT (0.79) | MAPTTHRBRORCSMN1; SMN2MEN1 | |
| SCHEMBL20031383 | 0.74 | NOTUM (0.56) | MAPTMAPK1USP30NPY5RSMN1; SMN2 | |
| SCHEMBL13901756 | 0.72 | RORC (0.73) | MAPTTHRBRORCSMN1; SMN2L3MBTL1 | |
| SCHEMBL13901733 | 0.72 | NPC1 (0.68) | MAPTTHRBRORCSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322429-A | Isoxazolylbenzamides as insecticides | ELI LILLY AND COMPANY (US) | 1982-03-30 | — | — | US | claimed |