Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.48 |
| ▸ | RORC | P51449 | 2/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.46 |
| ▸ | RORB | Q92753 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | KIT | P10721 | 2/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11272742 | 0.91 | USP30 (0.48) | USP30SMN1; SMN2EPAS1RORCRORB | |
| SCHEMBL11284045 | 0.87 | IL2 (0.57) | USP30SMN1; SMN2EPAS1RORCTLR7 | |
| SCHEMBL11296616 | 0.84 | SMN1; SMN2 (0.54) | USP30SMN1; SMN2RORCRAB9AMAPT | |
| SCHEMBL23973125 | 0.81 | USP30 (0.52) | USP30SMN1; SMN2MAPTKDRLMNA | |
| SCHEMBL11262815 | 0.81 | SMN1; SMN2 (0.49) | SMN1; SMN2RORCTLR7RAB9AMAPT | |
| SCHEMBL11293546 | 0.81 | SMN1; SMN2 (0.61) | USP30SMN1; SMN2RORCRAB9AMAPT | |
| SCHEMBL11301214 | 0.81 | RAB9A (0.55) | SMN1; SMN2EPAS1TLR7RORBRAB9A | |
| SCHEMBL13901759 | 0.79 | RORC (0.69) | SMN1; SMN2RORCRAB9AMAPTTHRB | |
| SCHEMBL23221331 | 0.76 | NPC1 (0.51) | USP30SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL11301018 | 0.75 | MAPT (0.59) | USP30SMN1; SMN2RORCRAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322429-A | Isoxazolylbenzamides as insecticides | ELI LILLY AND COMPANY (US) | 1982-03-30 | — | — | US | claimed |