Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 9/20 | 0.42 |
| ▸ | HTR2A | P28223 | 9/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11045867 | 0.80 | DRD2 (0.42) | DRD2DRD4DRD3HTR1AHTR2A | |
| SCHEMBL11045873 | 0.80 | DRD2 (0.42) | DRD2DRD4DRD3HTR1AHTR2A | |
| SCHEMBL11249933 | 0.79 | HTR1A (0.62) | HTR1A | |
| SCHEMBL4537434 | 0.74 | SLC6A4 (0.51) | DRD2DRD4DRD3HTR1AHTR2A | |
| SCHEMBL11244224 | 0.71 | HTR1A (0.51) | DRD2HTR1A | |
| SCHEMBL7186275 | 0.70 | KDM4E (0.46) | — | |
| SCHEMBL23175425 | 0.70 | DRD2 (0.46) | DRD2HTR1AHTR2A | |
| SCHEMBL15033122 | 0.70 | DRD2 (0.48) | DRD2HTR1AHTR2A | |
| SCHEMBL10637706 | 0.70 | DRD2 (0.55) | DRD2HTR1AHTR2A | |
| SCHEMBL10637150 | 0.70 | DRD2 (0.50) | DRD2HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4352811-A | NEUROLEPTIC AGENTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1982-10-05 | — | — | US | disclosed |