Fluoride Ion

Fluoride Ion

SCHEMBL1130163

C1=C([Zr+2]C2=Cc3ccccc3C2c2ccccc2)C(c2ccccc2)c2ccccc21.[F-].[F-]

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.32
TP53 P04637 2/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
MAPT P10636 1/20 0.32
MAPK1 P28482 1/20 0.32
HTR2B P41595 1/20 0.32
HTR2A P28223 1/20 0.31
ADRA2C P18825 1/20 0.30
PTGS2 P35354 1/20 0.30
HRH1 P35367 1/20 0.30
HTR3A P46098 1/20 0.30
PDE4D Q08499 1/20 0.30
GAA P10253 1/20 0.30
HPGD P15428 1/20 0.30
ALOX12 P18054 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7546508 0.77
Hydrochloric Acid SCHEMBL29871040 0.76
Fluoride Ion SCHEMBL27948730 0.74 LMNA (0.33) LMNATP53CYP1A2CYP3A4MAPT
Fluoride Ion SCHEMBL27932977 0.74 LMNA (0.33) LMNATP53CYP1A2CYP3A4MAPT
Fluoride Ion SCHEMBL1130750 0.72 DRD2 (0.38)
SCHEMBL3205637 0.72 LMNA (0.34) LMNATP53CYP1A2CYP3A4MAPT
SCHEMBL15661815 0.72 HDAC4 (0.38) LMNATP53CYP1A2CYP3A4MAPT
SCHEMBL29213168 0.72 LMNA (0.34) LMNATP53CYP1A2CYP3A4MAPT
SCHEMBL6673270 0.72 GAA (0.35) LMNATP53CYP1A2CYP3A4MAPT
SCHEMBL28219648 0.72 MEN1 (0.35) LMNATP53CYP1A2CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1673401-B1 POLYMERIZATION PROCESS AND CONTROL OF POLYMER COMPOSITION PROPERTIES UNIVATION TECH LLC (US) 2015-10-21 EP disclosed
EP-1546212-B1 BIMODAL POLYOLEFIN PRODUCTION PROCESS AND FILMS THEREFROM UNIVATION TECH LLC (US) 2011-02-16 EP disclosed
US-7238756-B2 Polymerization process and control of polymer composition properties UNIVATION TECHNOLOGIES, LLC (US) 2007-07-03 US disclosed
EP-1546212-A4 BIMODAL POLYOLEFIN PRODUCTION PROCESS AND FILMS THEREFROM UNIVATION TECH LLC (US) 2006-07-05 EP disclosed
CN-1708516-A Synthesis of polymerization catalyst components UNIVATION TECH LLC (US) 2005-12-14 CN disclosed
US-6943134-B2 Bimodal polyolefin production process and films therefrom UNIVATION TECHNOLOGIES, LLC (US) 2005-09-13 US disclosed
EP-1546212-A1 BIMODAL POLYOLEFIN PRODUCTION PROCESS AND FILMS THEREFROM Univation Technologies, LLC (US) 2005-06-29 EP disclosed
US-6884748-B2 Process for producing fluorinated catalysts UNIVATION TECHNOLOGIES, LLC (US) 2005-04-26 US disclosed
US-20050085600-A1 Polymerization process and control of polymer composition properties UNIVATION TECHNOLOGIES, LLC 2005-04-21 US disclosed
US-6875828-B2 Bimodal polyolefin production process and films therefrom UNIVATION TECHNOLOGIES, LLC (US) 2005-04-05 US disclosed
US-6869903-B2 Synthesis of polymerization catalyst components UNIVATION TECHNOLOGIES, LLC (US) 2005-03-22 US disclosed
US-20050054799-A1 Bimodal polyolefin production process and films therefrom KUO CHI-I (US) 2005-03-10 US disclosed
US-20050038210-A1 Bimodal polyolefin production process and films therefrom KUO CHI-I (US) 2005-02-17 US disclosed
US-6855784-B2 Synthesis of polymerization catalyst components UNIVATION TECHNOLOGIES, LLC (US) 2005-02-15 US disclosed
US-6828395-B1 Polymerization process and control of polymer composition properties UNIVATION TECHNOLOGIES, LLC 2004-12-07 US disclosed
US-20040236045-A1 SYNTHESIS OF POLYMERIZATION CATALYST COMPONENTS MATSUNAGA PHILLIP T (US) 2004-11-25 US disclosed
US-20040092387-A1 Synthesis of polymerization catalyst components UNIVATION TECHNOLOGIES, LLC 2004-05-13 US disclosed
WO-2004022607-A1 BIMODAL POLYOLEFIN PRODUCTION PROCESS AND FILMS THEREFROM UNIVATION TECHNOLOGIES, LLC (US) 2004-03-18 WO disclosed
US-20040044154-A1 Bimodal polyolefin production process and films therefrom UNIVATION TECHNOLOGIES, LLC 2004-03-04 US disclosed
US-20040043893-A1 Process for producing fluorinated catalysts UNIVATION TECHNOLOGIES, LLC 2004-03-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040043893-A1 Process for producing fluorinated catalysts FLI1, AFF1, INF2 LMNA 2788/4885TP53 375/4885CYP1A2 1339/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.