SCHEMBL11301669

SCHEMBL11301669

COc1ccc(C(=[N+]=[N-])c2ccc(OC)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.52
CES1 P23141 2/20 0.52
CA1 P00915 6/20 0.50
CA2 P00918 6/20 0.50
CA12 O43570 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
ALDH1A1 P00352 3/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
NR1I2 O75469 1/20 0.48
PRSS1 P07477 1/20 0.48
PRSS2 P07478 1/20 0.48
PRSS3 P35030 1/20 0.48
PARP1 P09874 1/20 0.48
PARP10 Q53GL7 1/20 0.48
PARP2 Q9UGN5 1/20 0.48
PARP4 Q9UKK3 1/20 0.48
KDM4E B2RXH2 2/20 0.47
MAPT P10636 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11302495 0.92 ACHE (0.58) CES2CES1CA1CA2CA12
SCHEMBL11301982 0.92 CES2 (0.58) CES2CES1CA1CA2ALDH1A1
SCHEMBL10469390 0.75 CES2 (0.58) CES2CES1SMN1; SMN2PRSS1PRSS2
SCHEMBL10467675 0.75 CES2 (0.53) CES2CES1ALDH1A1SMN1; SMN2PRSS1
SCHEMBL11301731 0.74 PARP10 (0.52) CA1CA2SMN1; SMN2PARP10TSHR
SCHEMBL11299641 0.74 HTT (0.49) CA1CA2CA12CA7CA9
SCHEMBL28400743 0.74 CA1 (0.57) CES2CES1CA1CA2ALDH1A1
SCHEMBL28497997 0.74 MAPT (0.46) CES2CES1CA1CA2CA12
SCHEMBL15992127 0.74 CES2 (0.64) CES2CES1CA1CA2PARP1
SCHEMBL16836046 0.74 CES2 (0.53) CES2CES1CA1CA2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118834308-A Preparation method of hydrogenated nitrile rubber with low Mooney viscosity 西安凯立新材料股份有限公司 2024-10-25 CN disclosed
US-4280819-A FUEL ADDITIVES ALSO FOR JET FUELS GULF RESEARCH & DEVELOPMENT COMPANY (US) 1981-07-28 US disclosed