Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11302847 | 0.81 | MAPT (0.56) | HTTMAPTNPSR1NPC1RAB9A | |
| SCHEMBL7190734 | 0.76 | TDP1 (0.43) | HTTMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL11804424 | 0.75 | HTT (0.62) | HTTMAPTNPSR1NPC1RAB9A | |
| SCHEMBL11301669 | 0.74 | CES2 (0.52) | MAPTNPSR1ALDH1A1HPGDMAPK1 | |
| SCHEMBL634335 | 0.73 | HTT (0.65) | HTTNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL1539315 | 0.73 | ALDH1A1 (0.67) | HTTMAPTNPSR1NPC1RAB9A | |
| SCHEMBL31003335 | 0.73 | ALDH1A1 (0.67) | HTTMAPTNPSR1NPC1RAB9A | |
| SCHEMBL16078417 | 0.73 | HTT (0.51) | HTTMAPTNPSR1NPC1RAB9A | |
| SCHEMBL1179412 | 0.72 | HTT (0.58) | HTTMAPTNPSR1NPC1RAB9A | |
| SCHEMBL1536363 | 0.72 | HTT (0.58) | HTTMAPTNPSR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4280819-A | FUEL ADDITIVES ALSO FOR JET FUELS | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1981-07-28 | — | — | US | disclosed |