Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 14/20 | 0.55 |
| ▸ | CA12 | O43570 | 13/20 | 0.55 |
| ▸ | CA1 | P00915 | 10/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.50 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.50 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.50 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11304655 | 0.97 | CA12 (0.52) | CA9CA12CA1MAPTPOLB | |
| SCHEMBL11304349 | 0.96 | CA12 (0.50) | CA9CA12CA1MAPTPOLB | |
| SCHEMBL11313919 | 0.95 | MAPT (0.51) | CA9CA12CA1MAPTPOLB | |
| SCHEMBL11308308 | 0.91 | ALDH1A1 (0.54) | MAPTGAANPSR1SMN1; SMN2RAB9A | |
| SCHEMBL11306073 | 0.91 | ALDH1A1 (0.48) | CA9CA12CA1MAPTPOLB | |
| SCHEMBL11312223 | 0.90 | MAPK1 (0.50) | CA9CA12CA1MAPTPOLB | |
| SCHEMBL11311312 | 0.89 | KMT2A (0.43) | CA9CA12CA1MAPTPOLB | |
| SCHEMBL11304549 | 0.86 | MAPK1 (0.48) | CA9CA12CA1MAPTPOLB | |
| SCHEMBL11305611 | 0.86 | MAPK1 (0.52) | CA9CA12CA1MAPTCA2 | |
| SCHEMBL11308024 | 0.85 | MAPT (0.62) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4283418-A | ANTIPLASMIN AND ANTITRYPSIN AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1981-08-11 | — | — | US | disclosed |