Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11312223 | 0.94 | MAPK1 (0.50) | MAPK1LMNASMN1; SMN2HTTMAPT | |
| SCHEMBL11313919 | 0.92 | MAPT (0.51) | LMNASMN1; SMN2HTTTP53MAPT | |
| SCHEMBL11306073 | 0.90 | ALDH1A1 (0.48) | LMNASMN1; SMN2KDM4EHTTTDP1 | |
| SCHEMBL11304655 | 0.90 | CA12 (0.52) | LMNASMN1; SMN2HTTMAPTKMT2A | |
| SCHEMBL11305611 | 0.89 | MAPK1 (0.52) | MAPK1LMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL11302014 | 0.86 | CA9 (0.55) | LMNASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL11313882 | 0.85 | KMT2A (0.40) | MAPK1LMNASMN1; SMN2HTTMAPT | |
| SCHEMBL11308024 | 0.85 | MAPT (0.62) | MAPK1SMN1; SMN2TP53MAPTKMT2A | |
| SCHEMBL11304349 | 0.84 | CA12 (0.50) | LMNASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL11308308 | 0.84 | ALDH1A1 (0.54) | MAPK1LMNASMN1; SMN2HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4283418-A | ANTIPLASMIN AND ANTITRYPSIN AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1981-08-11 | — | — | US | disclosed |