Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | ACR | P10323 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11311435 | 0.98 | MAPT (0.60) | MAPTSMN1; SMN2ALDH1A1HSD17B10TSHR | |
| SCHEMBL11302909 | 0.90 | ALDH1A1 (0.51) | MAPTSMN1; SMN2ALDH1A1HSD17B10TSHR | |
| SCHEMBL11305611 | 0.89 | MAPK1 (0.52) | MAPTSMN1; SMN2ALDH1A1TSHRPRSS1 | |
| SCHEMBL11310818 | 0.88 | SMN1; SMN2 (0.47) | MAPTSMN1; SMN2ALDH1A1HSD17B10PRSS1 | |
| SCHEMBL11304751 | 0.88 | SMN1; SMN2 (0.47) | MAPTSMN1; SMN2ALDH1A1TSHRPRSS1 | |
| SCHEMBL11308308 | 0.87 | ALDH1A1 (0.54) | MAPTSMN1; SMN2ALDH1A1TSHRKMT2A | |
| SCHEMBL11312223 | 0.87 | MAPK1 (0.50) | MAPTSMN1; SMN2ALDH1A1PRSS1ACR | |
| SCHEMBL11302014 | 0.85 | CA9 (0.55) | MAPTSMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL11304549 | 0.85 | MAPK1 (0.48) | MAPTSMN1; SMN2ALDH1A1PRSS1ACR | |
| SCHEMBL9717022 | 0.85 | PLG (0.60) | MAPTSMN1; SMN2ALDH1A1PRSS1ACR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4283418-A | ANTIPLASMIN AND ANTITRYPSIN AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1981-08-11 | — | — | US | claimed |
| JP-55115865-A | — | — | None | — | — | JP | disclosed |
| US-4283418-A | ANTIPLASMIN AND ANTITRYPSIN AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1981-08-11 | — | — | US | disclosed |
| JP-S55115865-A | GUANIDINOBENZOIC ACID DERIVATIVE AND ITS PREPARATION | ONO PHARMACEUT CO LTD | 1980-09-06 | — | — | JP | disclosed |