Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | PDE4A | P27815 | 1/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11611256 | 0.82 | SMN1; SMN2 (0.56) | ALDH1A1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL29405125 | 0.77 | MAPT (0.52) | ALDH1A1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL25260663 | 0.77 | MAPT (0.52) | ALDH1A1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL140231 | 0.76 | GAA (0.72) | ALDH1A1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL29702360 | 0.75 | LRRK2 (0.50) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL26100427 | 0.75 | LRRK2 (0.50) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL4238032 | 0.75 | RAB9A (0.76) | ALDH1A1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL29703258 | 0.75 | RAB9A (0.76) | ALDH1A1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL10507500 | 0.75 | NPBWR1 (0.51) | ALDH1A1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL10507488 | 0.75 | NPBWR1 (0.51) | ALDH1A1NPC1RAB9AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56061316-A | — | — | None | — | — | JP | disclosed |
| JP-S5661316-A | VASODILATOR | SHOWA DENKO KK | 1981-05-26 | — | — | JP | disclosed |