Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11206639 | 0.99 | GAA (0.34) | L3MBTL1GAATSHRTP53NPSR1 | |
| SCHEMBL11305248 | 0.88 | TSHR (0.36) | L3MBTL1TSHRTP53NPSR1ALDH1A1 | |
| SCHEMBL11312385 | 0.87 | L3MBTL1 (0.34) | L3MBTL1TSHRTP53NPSR1 | |
| SCHEMBL11307980 | 0.82 | GAA (0.31) | GAA | |
| SCHEMBL11227773 | 0.82 | MAPT (0.37) | L3MBTL1GAATSHRTP53NPSR1 | |
| SCHEMBL11197413 | 0.79 | SMN1; SMN2 (0.32) | ALDH1A1KDM4E | |
| SCHEMBL11307320 | 0.78 | — | — | |
| SCHEMBL11307840 | 0.77 | TSHR (0.38) | GAATSHRALDH1A1POLBKDM4E | |
| SCHEMBL11304955 | 0.75 | — | — | |
| SCHEMBL11376616 | 0.70 | NOD1 (0.33) | L3MBTL1GAATSHRTP53NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4316021-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1982-02-16 | — | — | US | disclosed |
| US-4243813-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1981-01-06 | — | — | US | disclosed |
| US-4196125-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1980-04-01 | — | — | US | disclosed |
| US-4118573-A | ANTIVIRAL AGENTS | ELI LILLY AND COMPANY (US) | 1978-10-03 | — | — | US | disclosed |
| US-4018790-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1977-04-19 | — | — | US | disclosed |