Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11312385 | 0.99 | L3MBTL1 (0.34) | TSHRL3MBTL1TP53NPSR1 | |
| SCHEMBL11304223 | 0.88 | L3MBTL1 (0.36) | TSHRL3MBTL1TP53NPSR1ALDH1A1 | |
| SCHEMBL11307840 | 0.88 | TSHR (0.38) | TSHRALDH1A1LMNAPOLB | |
| SCHEMBL11302734 | 0.82 | CYP3A4 (0.31) | — | |
| SCHEMBL11309668 | 0.81 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL11359715 | 0.80 | POLB (0.35) | TSHRL3MBTL1TP53NPSR1ALDH1A1 | |
| SCHEMBL11376616 | 0.79 | NOD1 (0.33) | TSHRL3MBTL1TP53NPSR1ALDH1A1 | |
| SCHEMBL11301376 | 0.77 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL11302735 | 0.77 | PI4KB (0.36) | — | |
| SCHEMBL11307520 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4316021-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1982-02-16 | — | — | US | disclosed |
| US-4243813-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1981-01-06 | — | — | US | disclosed |
| US-4196125-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1980-04-01 | — | — | US | disclosed |
| US-4118573-A | ANTIVIRAL AGENTS | ELI LILLY AND COMPANY (US) | 1978-10-03 | — | — | US | disclosed |
| US-4018790-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1977-04-19 | — | — | US | disclosed |