Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.44 |
| ▸ | ACR | P10323 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KLK1 | P06870 | 2/20 | 0.43 |
| ▸ | TMPRSS15 | P98073 | 4/20 | 0.43 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11308016 | 0.87 | KMT2A (0.47) | KMT2AMEN1MAPK1ALDH1A1MAPT | |
| SCHEMBL11313197 | 0.85 | KMT2A (0.48) | KMT2AMEN1MAPK1ALDH1A1MAPT | |
| SCHEMBL11313369 | 0.85 | TMPRSS15 (0.47) | KMT2AMEN1MAPK1ALDH1A1MAPT | |
| SCHEMBL11302255 | 0.84 | LMNA (0.52) | KMT2AMEN1MAPTPRSS1ACR | |
| SCHEMBL26047455 | 0.84 | KMT2A (0.52) | KMT2AMEN1MAPK1ALDH1A1MAPT | |
| SCHEMBL11313907 | 0.84 | PRSS1 (0.49) | KMT2AMEN1MAPK1ALDH1A1PRSS1 | |
| SCHEMBL20008699 | 0.83 | KMT2A (0.48) | KMT2AMEN1ALDH1A1PRSS1ACR | |
| SCHEMBL18720203 | 0.83 | KMT2A (0.48) | KMT2AMEN1ALDH1A1PRSS1ACR | |
| SCHEMBL11410222 | 0.83 | SMN1; SMN2 (0.50) | KMT2AMEN1MAPK1ALDH1A1MAPT | |
| SCHEMBL11306080 | 0.83 | KMT2A (0.46) | KMT2AMEN1MAPK1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4283418-A | ANTIPLASMIN AND ANTITRYPSIN AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1981-08-11 | — | — | US | disclosed |