Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.47 |
| ▸ | ACR | P10323 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 3/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.42 |
| ▸ | KLK1 | P06870 | 2/20 | 0.41 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.41 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18720203 | 1.00 | KMT2A (0.48) | KMT2APRSS1ACRMEN1SMN1; SMN2 | |
| SCHEMBL20008697 | 0.85 | PRSS1 (0.52) | PRSS1ACRF2PRSS2PRSS3 | |
| SCHEMBL18720209 | 0.85 | PRSS1 (0.52) | PRSS1ACRF2PRSS2PRSS3 | |
| SCHEMBL10956570 | 0.85 | KMT2A (0.56) | KMT2APRSS1ACRMEN1SMN1; SMN2 | |
| SCHEMBL26047455 | 0.84 | KMT2A (0.52) | KMT2APRSS1ACRMEN1SMN1; SMN2 | |
| SCHEMBL11304528 | 0.83 | KMT2A (0.44) | KMT2APRSS1ACRMEN1SMN1; SMN2 | |
| SCHEMBL11313907 | 0.83 | PRSS1 (0.49) | KMT2APRSS1ACRMEN1SMN1; SMN2 | |
| SCHEMBL1996805 | 0.83 | PRSS1 (0.60) | KMT2APRSS1ACRMEN1SMN1; SMN2 | |
| SCHEMBL7328271 | 0.83 | ACR (0.58) | KMT2APRSS1ACRMEN1SMN1; SMN2 | |
| SCHEMBL11410222 | 0.82 | SMN1; SMN2 (0.50) | KMT2APRSS1ACRMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180085366-A1 | OPIOID COMPOSITIONS RESISTANT TO OVERDOSE AND ABUSE | ELYSIUM THERAPEUTICS, INC. | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180085366-A1 | OPIOID COMPOSITIONS RESISTANT TO OVERDOSE AND ABUSE | OPRM1, OPRK1, OPRD1 | KMT2A 1946/4885PRSS1 952/4885ACR 4881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.