Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 4/20 | 0.56 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.56 |
| ▸ | TLR2 | O60603 | 10/20 | 0.56 |
| ▸ | PLA2G2C | Q5R387 | 3/20 | 0.52 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10819280 | 0.82 | ACHE (0.55) | LPAR1LPAR3TLR2LPAR2 | |
| SCHEMBL15158621 | 0.82 | ACHE (0.55) | LPAR1LPAR3TLR2LPAR2 | |
| SCHEMBL17431977 | 0.82 | ACHE (0.59) | LPAR1LPAR3TLR2 | |
| SCHEMBL15160079 | 0.82 | ACHE (0.55) | LPAR1LPAR3TLR2LPAR2 | |
| SCHEMBL23946005 | 0.82 | KDM4E (0.61) | — | |
| SCHEMBL18687261 | 0.82 | MMP9 (0.57) | TLR2PLA2G2C | |
| SCHEMBL31119611 | 0.81 | LPAR1 (0.59) | LPAR1LPAR3TLR2PLA2G2CLPAR2 | |
| SCHEMBL19123781 | 0.81 | ACHE (0.50) | LPAR1LPAR3TLR2LPAR2 | |
| SCHEMBL10819285 | 0.81 | ACHE (0.50) | LPAR1LPAR3TLR2LPAR2 | |
| SCHEMBL22930181 | 0.81 | ACHE (0.50) | LPAR1LPAR3TLR2LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4262021-A | INDUCERS OF PRODUCTION OF INTERFERON | PFIZER INC. (US) | 1981-04-14 | — | — | US | disclosed |
| US-4215146-A | Antiviral amine derivatives of glycerol and propanediols | PFIZER INC. (US) | 1980-07-29 | — | — | US | disclosed |
| US-4193999-A | Antiviral amine derivatives of propanediols | PFIZER INC. (US) | 1980-03-18 | — | — | US | disclosed |