Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 10/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.49 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.49 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.49 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22930181 | 1.00 | ACHE (0.50) | ACHETLR2LPAR1LPAR3LPAR2 | |
| SCHEMBL19123785 | 0.95 | TLR2 (0.49) | ACHETLR2LPAR1LPAR3LPAR2 | |
| SCHEMBL19932345 | 0.95 | TLR2 (0.49) | ACHETLR2LPAR1LPAR3LPAR2 | |
| SCHEMBL22930187 | 0.95 | TLR2 (0.49) | ACHETLR2LPAR1LPAR3LPAR2 | |
| SCHEMBL15158621 | 0.92 | ACHE (0.55) | ACHETLR2LPAR1LPAR3LPAR2 | |
| SCHEMBL10819280 | 0.92 | ACHE (0.55) | ACHETLR2LPAR1LPAR3LPAR2 | |
| SCHEMBL15160079 | 0.92 | ACHE (0.55) | ACHETLR2LPAR1LPAR3LPAR2 | |
| SCHEMBL17431977 | 0.92 | ACHE (0.59) | ACHETLR2LPAR1LPAR3 | |
| SCHEMBL10819285 | 0.90 | ACHE (0.50) | ACHETLR2LPAR1LPAR3LPAR2 | |
| SCHEMBL24470493 | 0.89 | LPAR1 (0.54) | ACHETLR2LPAR1LPAR3LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230255999-A1 | DNA COMPOSITIONS AND RELATED METHODS | FLAGSHIP PIONEERING INNOVATIONS VII, LLC | 2023-08-17 | — | — | US | disclosed |
| US-20230193311-A1 | IMMUNOGENIC COMPOSITIONS AND USES THEREOF | FLAGSHIP PIONEERING INNOVATIONS VI, LLC | 2023-06-22 | — | — | US | disclosed |
| US-20210078936-A1 | LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS | NOVARTIS AG (CH) | 2021-03-18 | — | — | US | disclosed |
| US-10792361-B2 | Lipids and lipid compositions for the delivery of active agents | NOVARTIS AG (CH) | 2020-10-06 | — | — | US | disclosed |
| US-10342761-B2 | Method of encapsulating a nucleic acid in a lipid nanoparticle host | NOVARTIS AG (CH) | 2019-07-09 | — | — | US | disclosed |
| US-20170196809-A1 | METHOD OF ENCAPSULATING A NUCLEIC ACID IN A LIPID NANOPARTICLE HOST | NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH INC. | 2017-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230193311-A1 | IMMUNOGENIC COMPOSITIONS AND USES THEREOF | MICA, CXCL10, HLA-DRB1 | ACHE 3694/4885TLR2 1171/4885LPAR1 3397/4885 |
| US-20230255999-A1 | DNA COMPOSITIONS AND RELATED METHODS | STING1, DNA2, TLR9 | ACHE 4572/4885TLR2 211/4885LPAR1 3388/4885 |
| US-20170196809-A1 | METHOD OF ENCAPSULATING A NUCLEIC ACID IN A LIPID NANOPARTICLE HOST | POLN, POLRMT, RNGTT | ACHE 4420/4885TLR2 2339/4885LPAR1 184/4885 |
| US-20210078936-A1 | LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS | LPAR1, LPAR4, LIPA | ACHE 2542/4885TLR2 2777/4885LPAR1 1/4885 |
| US-10342761-B2 | Method of encapsulating a nucleic acid in a lipid nanoparticle host | POLN, POLRMT, RNGTT | ACHE 4420/4885TLR2 2339/4885LPAR1 184/4885 |
| US-10792361-B2 | Lipids and lipid compositions for the delivery of active agents | LIPA, LPAR1, LPAR4 | ACHE 3437/4885TLR2 2041/4885LPAR1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.