Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26354730 | 0.78 | POLB (0.36) | ALDH1A1MAPTADORA2AADORA2BKDM4E | |
| SCHEMBL9034301 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL9035929 | 0.66 | CHRNB2 (0.40) | LMNAALDH1A1MAPTADORA2AADORA2B | |
| SCHEMBL21895488 | 0.66 | CDK1 (0.51) | APAF1CASP6CDK1LMNACYP3A4 | |
| SCHEMBL8696414 | 0.65 | TYMP (0.41) | APAF1CASP6LMNACYP3A4PMP22 | |
| SCHEMBL6577461 | 0.64 | TLR7 (0.52) | LMNACYP3A4PMP22KMT2AALDH1A1 | |
| SCHEMBL2948983 | 0.64 | ADORA2A (0.37) | LMNAKMT2AALDH1A1MAPTTSHR | |
| SCHEMBL28143896 | 0.63 | TYMP (0.40) | APAF1CASP6LMNACYP3A4PMP22 | |
| SCHEMBL1947320 | 0.62 | ADORA2B (0.39) | APAF1CASP6LMNACYP3A4PMP22 | |
| SCHEMBL10379715 | 0.62 | MAOA (0.33) | LMNAKMT2AALDH1A1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56051481-A | — | — | None | — | — | JP | disclosed |
| JP-S5651481-A | 6-CYANO-2-OXO-3-METHYL-2,3-DIHYDROPURINE | SAGAMI CHEM RES CENTER | 1981-05-09 | — | — | JP | disclosed |