Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.71 |
| ▸ | LMNA | P02545 | 4/20 | 0.71 |
| ▸ | POLB | P06746 | 2/20 | 0.71 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5265296 | 0.86 | LMNA (0.81) | SMN1; SMN2LMNAPOLBRXFP1GAA | |
| SCHEMBL11308689 | 0.84 | MAPK1 (0.61) | SMN1; SMN2LMNAPOLBRXFP1MAPK1 | |
| Dyphylline SCHEMBL123781 | 0.83 | LMNA (1.00) | SMN1; SMN2LMNAPOLBRXFP1GAA | |
| SCHEMBL10063431 | 0.83 | LMNA (0.80) | SMN1; SMN2LMNAPOLBRXFP1GAA | |
| Dyphylline SCHEMBL1816552 | 0.83 | LMNA (1.00) | SMN1; SMN2LMNAPOLBRXFP1GAA | |
| Dyphylline SCHEMBL8192 | 0.83 | LMNA (1.00) | SMN1; SMN2LMNAPOLBRXFP1GAA | |
| SCHEMBL10967382 | 0.83 | MAPK1 (0.82) | SMN1; SMN2LMNAPOLBRXFP1MAPK1 | |
| SCHEMBL11601258 | 0.82 | LMNA (0.78) | SMN1; SMN2LMNAPOLBRXFP1GAA | |
| SCHEMBL10768492 | 0.82 | LMNA (0.78) | SMN1; SMN2LMNAPOLBRXFP1GAA | |
| SCHEMBL11757490 | 0.82 | LMNA (0.78) | SMN1; SMN2LMNAPOLBRXFP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56145287-A | — | — | None | — | — | JP | disclosed |
| JP-S56145287-A | XANTHINE DERIVATIVE AND ITS PREPARATION | NIPPON IYAKUHIN KAIHATSU KENKYUSHO:KK | 1981-11-11 | — | — | JP | disclosed |