Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.81 |
| ▸ | POLB | P06746 | 2/20 | 0.81 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.68 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dyphylline SCHEMBL1816552 | 0.89 | LMNA (1.00) | LMNASMN1; SMN2POLBADORA2BRXFP1 | |
| Dyphylline SCHEMBL8192 | 0.89 | LMNA (1.00) | LMNASMN1; SMN2POLBADORA2BRXFP1 | |
| Dyphylline SCHEMBL123781 | 0.89 | LMNA (1.00) | LMNASMN1; SMN2POLBADORA2BRXFP1 | |
| Dyphylline SCHEMBL27937456 | 0.88 | LMNA (0.97) | LMNASMN1; SMN2POLBADORA2BRXFP1 | |
| SCHEMBL10063431 | 0.86 | LMNA (0.80) | LMNASMN1; SMN2POLBADORA2BRXFP1 | |
| SCHEMBL11305096 | 0.86 | SMN1; SMN2 (0.71) | LMNASMN1; SMN2POLBADORA2BRXFP1 | |
| SCHEMBL10768492 | 0.85 | LMNA (0.78) | LMNASMN1; SMN2POLBADORA2BRXFP1 | |
| SCHEMBL11601258 | 0.85 | LMNA (0.78) | LMNASMN1; SMN2POLBADORA2BRXFP1 | |
| SCHEMBL11757490 | 0.85 | LMNA (0.78) | LMNASMN1; SMN2POLBADORA2BRXFP1 | |
| SCHEMBL13944619 | 0.85 | LMNA (0.81) | LMNASMN1; SMN2POLBADORA2BRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1829523-A1 | Cosmetic use of an N-oxide derivative of theophylline | L'OREAL (FR) | 2007-09-05 | — | — | EP | disclosed |