Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.37 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL472903 | 1.00 | NOD1 (0.40) | NOD1GRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL11305652 | 0.83 | GRIK1 (0.40) | NOD1GRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL19859237 | 0.81 | NOD1 (0.47) | NOD1GRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL9634474 | 0.80 | NOD1 (0.49) | NOD1GRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL9634471 | 0.80 | NOD1 (0.49) | NOD1GRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL8934208 | 0.79 | GPR84 (0.38) | NOD1GRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL8934205 | 0.79 | GPR84 (0.38) | NOD1GRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL341674 | 0.79 | NOD1 (0.51) | NOD1GRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL11308884 | 0.79 | GRIK1 (0.42) | GRIK1GRIK2SLC1A2SLC1A1SLC6A5 | |
| SCHEMBL1031164 | 0.79 | NOD1 (0.51) | NOD1GRIK1GRIK2SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5401491-A | NMR contrast agents | GUERBET S.A. (FR) | 1995-03-28 | — | — | US | disclosed |
| EP-0183760-B1 | NMR CONTRAST AGENTS | GUERBET S.A. (FR) | 1992-03-18 | — | — | EP | disclosed |
| EP-0183760-A1 | NMR CONTRAST AGENTS. | AMERSHAM INT PLC (GB) | 1986-06-11 | — | — | EP | disclosed |
| WO-1985005554-A1 | NMR CONTRAST AGENTS | AMERSHAM INTERNATIONAL PLC (GB) | 1985-12-19 | — | — | WO | disclosed |