Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11301999 | 0.86 | GABBR2 (0.41) | ESR1RXRANR1H4CA1CA2 | |
| SCHEMBL2389161 | 0.82 | ESR1 (0.43) | ESR1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL699096 | 0.76 | GABBR2 (0.40) | ESR1RXRANR1H4PTGER1PTGER4 | |
| SCHEMBL180577 | 0.75 | ESR1 (0.38) | ESR1RXRANR1H4CYP1A2KDM4E | |
| SCHEMBL11131914 | 0.74 | ESR1 (0.34) | ESR1RXRANR1H4PTGER1PTGER4 | |
| SCHEMBL696524 | 0.71 | GABBR2 (0.38) | ESR1RXRANR1H4CA1CA2 | |
| SCHEMBL22991749 | 0.71 | CA1 (0.43) | ESR1RXRANR1H4PTGER1PTGER4 | |
| SCHEMBL30555699 | 0.71 | CA1 (0.43) | ESR1RXRANR1H4PTGER1PTGER4 | |
| SCHEMBL2392799 | 0.70 | PTGER3 (0.38) | ESR1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL698507 | 0.69 | GABBR2 (0.36) | ESR1RXRANR1H4CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4281080-A | TACKIFIERS FOR RUBBERS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1981-07-28 | — | — | US | disclosed |
| US-4010140-A | Age resistant resin compositions and admixtures useful as adhesives | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1977-03-01 | — | — | US | disclosed |