SCHEMBL180577

SCHEMBL180577

CCCCCCCCCCCCCCCCCCc1c(C=CC(=O)O)cc(C(C)(C)C)c(O)c1C(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.38
ATG4B Q9Y4P1 11/20 0.37
PLA2G1B P04054 9/20 0.37
THRA P10827 1/20 0.37
THRB P10828 1/20 0.37
CYP1A2 P05177 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
RECQL P46063 1/20 0.37
GABBR2 O75899 1/20 0.36
GABBR1 Q9UBS5 1/20 0.36
TNFRSF1A P19438 1/20 0.36
RXRA P19793 2/20 0.36
NR1H4 Q96RI1 1/20 0.36
KDM4E B2RXH2 1/20 0.36
NPC1 O15118 1/20 0.36
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36
CASP3 P42574 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL699096 0.95 GABBR2 (0.40) ESR1CYP1A2GABBR2GABBR1TNFRSF1A
Phenol SCHEMBL28850520 0.94 ESR1 (0.40) ESR1ATG4BPLA2G1BTHRATHRB
SCHEMBL10530884 0.85 GABBR2 (0.37) CYP1A2TDP1RECQLGABBR2GABBR1
SCHEMBL11301999 0.85 GABBR2 (0.41) ESR1CYP1A2RECQLGABBR2GABBR1
SCHEMBL696524 0.83 GABBR2 (0.38) ESR1CYP1A2GABBR2GABBR1TNFRSF1A
SCHEMBL205695 0.79 KAT8 (0.45)
SCHEMBL226460 0.79 KAT8 (0.45)
SCHEMBL19951468 0.79 KAT8 (0.45)
SCHEMBL227902 0.79 KAT8 (0.45)
SCHEMBL223272 0.79 KAT8 (0.45)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 500 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12637557-B2 High crystalline olefin polymer for high speed spinning W.R. GRACE & CO.-CONN. (US) 2026-05-26 US disclosed
US-12617984-B2 Hydrophilic hotmelt adhesive THE PROCTER & GAMBLE COMPANY (US) 2026-05-05 US disclosed
US-12570785-B2 Thermoplastic polyurethane resin elastomers MITSUBISHI CHEMICAL CORPORATION (JP) 2026-03-10 US disclosed
US-20260008875-A1 ETHYLENE-BASED POLYMER WITH REVERSIBLE CROSSLINKER DOW GLOBAL TECHNOLOGIES LLC (US) 2026-01-08 US disclosed
US-20260008879-A1 POLAR ETHYLENE-BASED POLYMER WITH REVERSIBLE CROSSLINKNER DOW GLOBAL TECHNOLOGIES LLC (US) 2026-01-08 US disclosed
US-20260008896-A1 REVERSIBLE CROSSLINKED FOAM ARTICLE AND PROCESS DOW GLOBAL TECHNOLOGIES LLC (US) 2026-01-08 US disclosed
EP-4259699-B1 HIGH CRYSTALLINE OLEFIN POLYMER FOR HIGH SPEED SPINNING GRACE W R & CO (US) 2025-10-22 EP disclosed
EP-3781105-B1 ABSORBENT ARTICLE COMPRISING AN ADHESIVE COMPOSITION PROCTER & GAMBLE (US) 2025-08-13 EP disclosed
EP-3390475-B1 CROSS-LINKED FOAMS MADE FROM INTERPOLYMERS OF ETHYLENE/ALPHA-OLEFINS DOW GLOBAL TECHNOLOGIES LLC (US) 2025-05-21 EP disclosed
US-12233170-B2 Absorbent article comprising a lotion resistant polymeric filler composition THE PROCTER & GAMBLE COMPANY (US) 2025-02-25 US disclosed
US-20060199908-A1 Rheology modification of interpolymers of ethylene/alpha-olefins and articles made therefrom DOW GLOBAL TECHNOLOGIES INC. (US) 2006-09-07 US disclosed
US-20060199897-A1 Adhesive and marking compositions made from interpolymers of ethylene/alpha-olefins DOW GLOBAL TECHNOLOGIES INC. (US) 2006-09-07 US disclosed
US-20060199872-A1 Foams made from interpolymers of ethylene/alpha-olefins DOW GLOBAL TECHNOLOGIES INC. (US) 2006-09-07 US disclosed
US-20060198983-A1 Three dimensional random looped structures made from interpolymers of ethylene/alpha-olefins and uses thereof DOW GLOBAL TECHNOLOGIES INC. (US) 2006-09-07 US disclosed
US-20050250907-A1 Dispersant or coatability improver SANYO CHEMICAL INDUSTRIES LTD., (JP) 2005-11-10 US disclosed
EP-1579907-A2 Dispersant or coatability improver SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2005-09-28 EP disclosed
US-20050009967-A1 Phosphite stabilizers and methods to preparation and polymer composition thereof CROMPTON CORPORATION 2005-01-13 US disclosed
WO-2004111158-A1 PHOSPHITE STABILIZERS AND METHODS TO PREPARATION AND POLYMER COMPOSITION THEREOF CHEMTURA CORPORATION (US) 2004-12-23 WO disclosed
WO-2004108735-A2 POLYMER COMPOSITIONS CONTAINING STABILIZER COMPOUNDS COMPRISING TRICYCLODECILMETHYL GROUPS CHEMTURA CORPORATION (US) 2004-12-16 WO disclosed
US-20040249030-A1 Polymer compositions containing stabilizer compounds comprising tricyclodecylmethyl groups ADDIVANT USA, LLC 2004-12-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008875-A1 ETHYLENE-BASED POLYMER WITH REVERSIBLE CROSSLINKER CLPTM1L, LCP1, CLPTM1 ESR1 12/4885ATG4B 1522/4885PLA2G1B 1825/4885
US-12570785-B2 Thermoplastic polyurethane resin elastomers PUF60, INTS9, ADH1C ESR1 1500/4885ATG4B 2450/4885PLA2G1B 2107/4885
US-12637557-B2 High crystalline olefin polymer for high speed spinning DYRK1B, DYRK3, TARDBP ESR1 3240/4885ATG4B 2865/4885PLA2G1B 2314/4885
US-20050009967-A1 Phosphite stabilizers and methods to preparation and polymer composition thereof PHOSPHO1, OR51E2, CDIPT ESR1 2287/4885ATG4B 3499/4885PLA2G1B 1531/4885
US-20060199897-A1 Adhesive and marking compositions made from interpolymers of ethylene/alpha-olefins ICAM1, COL1A1, TMT1A ESR1 128/4885ATG4B 2905/4885PLA2G1B 3953/4885
US-12617984-B2 Hydrophilic hotmelt adhesive EPCAM, PMS2, L1CAM ESR1 615/4885ATG4B 2327/4885PLA2G1B 2465/4885
US-20260008896-A1 REVERSIBLE CROSSLINKED FOAM ARTICLE AND PROCESS PIEZO1, AIFM2, PTDSS1 ESR1 751/4885ATG4B 3029/4885PLA2G1B 1864/4885
US-20260008879-A1 POLAR ETHYLENE-BASED POLYMER WITH REVERSIBLE CROSSLINKNER EEA1, EED, ELP1 ESR1 8/4885ATG4B 3529/4885PLA2G1B 1687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.