SCHEMBL11307142

SCHEMBL11307142

CCOC(=O)NCCOc1ccc(Cc2ccccc2)cc1

nearest known ligand 0.76

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.70
MAPT P10636 1/20 0.70
LTA4H P09960 14/20 0.69
KDM4E B2RXH2 1/20 0.55
GLA P06280 1/20 0.53
KMT2A Q03164 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8603693 0.89 MTNR1A (0.66) L3MBTL1MAPTLTA4HKDM4E
SCHEMBL11311557 0.88 L3MBTL1 (0.59) L3MBTL1MAPTLTA4HGLAKMT2A
Phenoxycarb SCHEMBL27336 0.86 L3MBTL1 (0.62) L3MBTL1MAPTLTA4HKDM4E
Phenoxycarb SCHEMBL7944821 0.86 L3MBTL1 (0.62) L3MBTL1MAPTLTA4HKDM4E
SCHEMBL11305599 0.84 L3MBTL1 (0.60) L3MBTL1MAPTLTA4HKDM4EKMT2A
SCHEMBL10895637 0.83 ALDH1A1 (0.72) L3MBTL1MAPTLTA4HKDM4EGLA
SCHEMBL11886540 0.83 NPC1 (0.65) L3MBTL1MAPTGLAKMT2A
SCHEMBL11308868 0.83 L3MBTL1 (0.58) L3MBTL1MAPTLTA4HKDM4EGLA
Phenoxycarb SCHEMBL6267309 0.83 L3MBTL1 (0.58) L3MBTL1MAPTLTA4HKDM4E
SCHEMBL10877494 0.82 L3MBTL1 (0.57) L3MBTL1MAPTLTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0004334-B1 CARBAMATES AND THEIR PESTICIDAL COMPOSITIONS, PREPARATIONS THEREOF AND USE THEREOF AS PESTICIDES F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1981-10-21 EP claimed
US-4215139-A PESTICIDES, INSECTICIDES HOFFMANN-LA ROCHE INC. (US) 1980-07-29 US claimed
US-4215139-A PESTICIDES, INSECTICIDES HOFFMANN-LA ROCHE INC. (US) 1980-07-29 US disclosed