Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.49 |
| ▸ | S100A4 | P26447 | 2/20 | 0.49 |
| ▸ | PTPRC | P08575 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA9 | Q16790 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11755401 | 0.83 | LMNA (0.55) | TNFS100A4PTPRCLMNATDP1 | |
| SCHEMBL31259816 | 0.83 | LMNA (0.55) | TNFS100A4PTPRCLMNATDP1 | |
| SCHEMBL5600105 | 0.78 | TNF (0.45) | TNFS100A4PTPRCLMNATDP1 | |
| SCHEMBL16065036 | 0.78 | L3MBTL1 (0.57) | LMNATDP1KDM4ECYP1A2CYP2C19 | |
| SCHEMBL23513454 | 0.77 | TNF (0.50) | TNFS100A4PTPRCLMNATDP1 | |
| SCHEMBL7736757 | 0.77 | LMNA (0.52) | TNFS100A4PTPRCLMNATDP1 | |
| SCHEMBL6925259 | 0.77 | LMNA (0.52) | TNFS100A4PTPRCLMNATDP1 | |
| SCHEMBL6925120 | 0.77 | LMNA (0.52) | TNFS100A4PTPRCLMNATDP1 | |
| SCHEMBL19359510 | 0.77 | KMT2A (0.50) | TNFS100A4PTPRCLMNACA2 | |
| SCHEMBL11313549 | 0.77 | TNF (0.42) | TNFS100A4PTPRCLMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001597-B1 | UNDER LIGHT EXPOSURE HARDENABLE, BIS-AZIDOPHTHALIMIDYL COMPOUNDS CONTAINING COMPOSITIONS | CIBA-GEIGY AG (CH) | 1981-10-21 | — | — | EP | disclosed |
| EP-0002182-B1 | BIS-AZIDO-PHTHALIC ACID DERIVATIVES AND PROCESS FOR THEIR PREPARATION | CIBA-GEIGY AG (CH) | 1981-04-08 | — | — | EP | disclosed |
| US-4197133-A | Photo-curable compositions of matter containing bis-azidophthalimidyl derivatives | CIBA-GEIGY CORPORATION (US) | 1980-04-08 | — | — | US | disclosed |
| EP-0002182-A2 | Bis-azido-phthalic acid derivatives and process for their preparation | CIBA-GEIGY AG (CH) | 1979-06-13 | — | — | EP | disclosed |
| EP-0001597-A1 | Under light exposure hardenable, bis-azidophthalimidyl compounds containing compositions | CIBA-GEIGY AG (CH) | 1979-05-02 | — | — | EP | disclosed |