SCHEMBL11307352

SCHEMBL11307352

CCOC(=O)Cc1ccc(Sc2ccccc2)cc1OC

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
TUBB4A P04350 2/20 0.46
TUBB P07437 2/20 0.46
TUBA3C P0DPH7 2/20 0.46
TUBA1B P68363 2/20 0.46
TUBA4A P68366 2/20 0.46
TUBB4B P68371 2/20 0.46
TUBB3 Q13509 2/20 0.46
TUBB2A Q13885 2/20 0.46
TUBB8 Q3ZCM7 2/20 0.46
TUBA3E Q6PEY2 2/20 0.46
TUBA1A Q71U36 2/20 0.46
TUBA1C Q9BQE3 2/20 0.46
TUBB6 Q9BUF5 2/20 0.46
TUBB2B Q9BVA1 2/20 0.46
TUBB1 Q9H4B7 2/20 0.46
MAPT P10636 2/20 0.45
LMNA P02545 1/20 0.45
PKM P14618 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11297053 0.85 L3MBTL1 (0.49) L3MBTL1SMN1; SMN2TUBB4ATUBBTUBA3C
SCHEMBL11307557 0.83 L3MBTL1 (0.47) L3MBTL1SMN1; SMN2TUBB4ATUBBTUBA3C
SCHEMBL21438503 0.80 RECQL (0.46) L3MBTL1SMN1; SMN2MAPTLMNAPKM
SCHEMBL11301101 0.78 L3MBTL1 (0.54) L3MBTL1SMN1; SMN2TUBB4ATUBBTUBA3C
SCHEMBL2064203 0.78 DPP4 (0.48) L3MBTL1SMN1; SMN2PKMDPP4ALDH1A1
SCHEMBL1792326 0.77 TSHR (0.55) L3MBTL1SMN1; SMN2MAPTLMNAPKM
SCHEMBL14572092 0.77 MAPK1 (0.46) L3MBTL1SMN1; SMN2MAPTLMNAPKM
SCHEMBL31395505 0.76 EGFR (0.51) DPP4ALDH1A1MEN1KMT2AKDM4E
SCHEMBL21455751 0.76 ALDH1A1 (0.53) MAPTDPP4ALDH1A1PPARGMEN1
SCHEMBL30482840 0.76 ALDH1A1 (0.53) MAPTDPP4ALDH1A1PPARGMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4287355-A USED TO RETARD PASSAGE OF GLUCOSE INTO THE BLOOD SANDOZ, INC. (US) 1981-09-01 US disclosed