Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.40 |
| ▸ | TUBB | P07437 | 2/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11304499 | 0.90 | MAPT (0.43) | L3MBTL1SMN1; SMN2MAPTLMNAALDH1A1 | |
| SCHEMBL11307557 | 0.86 | L3MBTL1 (0.47) | L3MBTL1SMN1; SMN2MAPTLMNAALDH1A1 | |
| SCHEMBL11307352 | 0.85 | L3MBTL1 (0.46) | L3MBTL1SMN1; SMN2MAPTLMNAALDH1A1 | |
| SCHEMBL11301101 | 0.81 | L3MBTL1 (0.54) | L3MBTL1SMN1; SMN2MAPTLMNAALDH1A1 | |
| SCHEMBL15933303 | 0.80 | HPGD (0.47) | L3MBTL1SMN1; SMN2MAPTLMNAALDH1A1 | |
| SCHEMBL14572092 | 0.80 | MAPK1 (0.46) | L3MBTL1SMN1; SMN2MAPTLMNAALDH1A1 | |
| SCHEMBL11130792 | 0.78 | L3MBTL1 (0.42) | L3MBTL1SMN1; SMN2MAPTLMNAALDH1A1 | |
| SCHEMBL29668340 | 0.76 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTALDH1A1PKMHSD17B10 | |
| SCHEMBL27741997 | 0.76 | ALDH1A1 (0.46) | SMN1; SMN2MAPTALDH1A1HPGDTDP1 | |
| SCHEMBL16673261 | 0.76 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTALDH1A1PKMHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4287355-A | USED TO RETARD PASSAGE OF GLUCOSE INTO THE BLOOD | SANDOZ, INC. (US) | 1981-09-01 | — | — | US | disclosed |