Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 8/20 | 0.51 |
| ▸ | PTGFR | P43088 | 8/20 | 0.51 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.51 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.51 |
| ▸ | SLCO2A1 | Q92959 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.44 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11304538 | 1.00 | TBXA2R (0.51) | TBXA2RPTGFRPTGER3LMNAPTGER1 | |
| SCHEMBL11444957 | 0.85 | TBXA2R (0.53) | TBXA2RPTGFRPTGER3LMNAPTGER1 | |
| SCHEMBL11299727 | 0.84 | TBXA2R (0.54) | TBXA2RPTGFRPTGER3LMNAPTGER1 | |
| SCHEMBL11478262 | 0.84 | TBXA2R (0.54) | TBXA2RPTGFRPTGER3LMNAPTGER1 | |
| SCHEMBL10631786 | 0.84 | ALDH1A1 (0.53) | TBXA2RPTGFRPTGER3LMNAPTGER1 | |
| SCHEMBL9480759 | 0.84 | ALDH1A1 (0.53) | TBXA2RPTGFRPTGER3LMNAPTGER1 | |
| SCHEMBL10631782 | 0.84 | ALDH1A1 (0.53) | TBXA2RPTGFRPTGER3LMNAPTGER1 | |
| SCHEMBL9480769 | 0.84 | ALDH1A1 (0.53) | TBXA2RPTGFRPTGER3LMNAPTGER1 | |
| SCHEMBL11372858 | 0.84 | TBXA2R (0.43) | TBXA2RPTGFRPTGER3LMNAPTGER1 | |
| SCHEMBL11367013 | 0.84 | TBXA2R (0.43) | TBXA2RPTGFRPTGER3LMNAPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4256911-A | TRIFLUOROMETHYL-CARBOXY ESTERS | HOFFMANN-LA ROCHE INC. (US) | 1981-03-17 | — | — | US | disclosed |
| US-4237276-A | CARDIOVASCULAR AGENTS, INDUCTION OF LABOR, TERMINATION OF PREGNANCY | HOFFMANN-LA ROCHE INC. (US) | 1980-12-02 | — | — | US | disclosed |
| US-4211724-A | ENANTIOMORPHS, INTERMEDIATE AMIDES WITH ASSYMETRIC CARBON ATOM | HOFFMAN-LA ROCHE INC. (US) | 1980-07-08 | — | — | US | disclosed |
| US-4190587-A | PROSTAGLANDINS | HOFFMANN-LA ROCHE INC. (US) | 1980-02-26 | — | — | US | disclosed |
| US-4187381-A | CARDIOVASCULAR AGENTS; OXYTOCICS | HOFFMANN-LA ROCHE INC. (US) | 1980-02-05 | — | — | US | disclosed |
| US-4112225-A | 16-CF3 prostaglandins | HOFFMAN-LA ROCHE INC. (US) | 1978-09-05 | — | — | US | disclosed |