Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 8/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | F2R | P25116 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11035760 | 0.86 | NLRP3 (0.48) | NLRP3SMN1; SMN2KDM4ECYP1A2CYP2C9 | |
| SCHEMBL11326131 | 0.83 | NLRP3 (0.41) | NLRP3SMN1; SMN2KDM4ECYP1A2CYP2C9 | |
| SCHEMBL11546525 | 0.80 | NLRP3 (0.49) | NLRP3SMN1; SMN2KDM4ECYP1A2CYP2C9 | |
| SCHEMBL11545247 | 0.79 | GSK3B (0.42) | SMN1; SMN2KDM4EHPGDPOLBHSD17B10 | |
| SCHEMBL1000325 | 0.76 | NLRP3 (0.59) | NLRP3SMN1; SMN2KDM4ECYP1A2CYP2C9 | |
| SCHEMBL11547384 | 0.73 | GSK3B (0.37) | NLRP3KDM4EKMT2AMEN1HPGD | |
| SCHEMBL11552739 | 0.72 | GSK3B (0.44) | HPGDLMNAGSK3B | |
| SCHEMBL26588963 | 0.72 | NLRP3 (0.78) | NLRP3SMN1; SMN2KDM4ECYP1A2CYP2C9 | |
| SCHEMBL30741281 | 0.71 | NLRP3 (0.48) | NLRP3SMN1; SMN2KDM4ECYP1A2CYP2C9 | |
| SCHEMBL11956604 | 0.71 | GSK3B (0.54) | KMT2AMEN1MAPTGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0057900-A1 | Animal feed additive for improving growth | Dr. Karl Thomae GmbH (DE) | 1982-08-18 | — | — | EP | disclosed |
| EP-0008715-B1 | PHENYLETHANOLAMINES FOR USE IN COMBATTING INFLAMMATORY CONDITIONS | Dr. Karl Thomae GmbH (DE) | 1981-11-25 | — | — | EP | disclosed |
| US-4244967-A | ANTIIFLAMMATORY AND ANTIRHEUMATIC PROPERTIES | BOEHRINGER INGELHEIM GMBH (DE) | 1981-01-13 | — | — | US | disclosed |
| US-4214001-A | ANALGESICS, ANTISPASMODICS AND ANTIASTHMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1980-07-22 | — | — | US | disclosed |
| EP-0008715-A1 | Phenylethanolamines for use in combatting inflammatory conditions | Dr. Karl Thomae GmbH (DE) | 1980-03-19 | — | — | EP | disclosed |