Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11547384 | 0.90 | GSK3B (0.37) | GSK3BALDH1A1KDM4EUSP2POLB | |
| SCHEMBL11552737 | 0.83 | GSK3B (0.42) | GSK3BALDH1A1PTPN1KDM4EUSP2 | |
| SCHEMBL11547125 | 0.81 | SMN1; SMN2 (0.41) | ALDH1A1KDM4EUSP2POLBHSD17B10 | |
| SCHEMBL11308142 | 0.79 | NLRP3 (0.46) | GSK3BKDM4EPOLBHSD17B10HPGD | |
| SCHEMBL11552739 | 0.79 | GSK3B (0.44) | GSK3BALDH1A1PTPN1HPGD | |
| SCHEMBL21373264 | 0.75 | GSK3B (0.52) | GSK3BALDH1A1PTPN1HSD17B10HPGD | |
| SCHEMBL1198090 | 0.72 | GSK3B (0.58) | GSK3BALDH1A1PTPN1HPGDRAB9A | |
| SCHEMBL11549836 | 0.72 | HPGD (0.39) | GSK3BALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL11546525 | 0.72 | NLRP3 (0.49) | GSK3BALDH1A1KDM4EPOLBHPGD | |
| SCHEMBL11546761 | 0.71 | ALDH1A1 (0.40) | ALDH1A1KDM4EUSP2POLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145363-A | ANTIASTHMATICS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1979-03-20 | — | — | US | disclosed |
| US-4063025-A | PROPHYLAXIS, ANTIASTHMATIC | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) | 1977-12-13 | — | — | US | disclosed |