Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11552737 | 0.93 | GSK3B (0.42) | GSK3BALDH1A1KDM4EGAATSHR | |
| SCHEMBL11545247 | 0.90 | GSK3B (0.42) | GSK3BALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL11546761 | 0.84 | ALDH1A1 (0.40) | ALDH1A1KDM4EGAATSHRPDE4D | |
| SCHEMBL11546525 | 0.81 | NLRP3 (0.49) | GSK3BALDH1A1KDM4ETSHRMEN1 | |
| SCHEMBL11549836 | 0.81 | HPGD (0.39) | GSK3BALDH1A1KDM4EGAATSHR | |
| SCHEMBL11545239 | 0.80 | HPGD (0.43) | GSK3BKDM4ETSHRMEN1KMT2A | |
| SCHEMBL11546203 | 0.79 | HPGD (0.44) | GSK3BALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL11546286 | 0.76 | GSK3B (0.41) | GSK3BALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL11546340 | 0.75 | GSK3B (0.45) | GSK3BALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL11545577 | 0.75 | GSK3B (0.43) | GSK3BALDH1A1KDM4EGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145363-A | ANTIASTHMATICS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1979-03-20 | — | — | US | disclosed |
| US-4063025-A | PROPHYLAXIS, ANTIASTHMATIC | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) | 1977-12-13 | — | — | US | disclosed |