Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | S100A4 | P26447 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | PLK1 | P53350 | 1/20 | 0.30 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11309414 | 0.90 | MAPT (0.35) | MAPTNPSR1PABPC1GAAMEN1 | |
| SCHEMBL13525232 | 0.88 | MAPT (0.37) | MAPTNPSR1PABPC1GAAMEN1 | |
| SCHEMBL13206444 | 0.88 | MAPT (0.36) | MAPTNPSR1GAAMEN1RAB9A | |
| SCHEMBL92422 | 0.88 | MAPT (0.36) | MAPTNPSR1GAAMEN1RAB9A | |
| SCHEMBL11323978 | 0.87 | MAPT (0.35) | MAPTNPSR1PABPC1GAAMEN1 | |
| SCHEMBL10000296 | 0.86 | MEN1 (0.33) | MAPTMEN1RAB9AKMT2ALMNA | |
| SCHEMBL11414969 | 0.84 | MAPT (0.36) | MAPTNPSR1GAAMEN1RAB9A | |
| SCHEMBL10000294 | 0.84 | MAPT (0.33) | MAPTGAAMEN1RAB9AKMT2A | |
| SCHEMBL11330897 | 0.83 | PABPC1 (0.53) | MAPTNPSR1PABPC1GAAMEN1 | |
| SCHEMBL12832322 | 0.82 | MAPT (0.34) | MAPTNPSR1GAAMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4248591-A | HAIR DYES | L'OREAL (FR) | 1981-02-03 | — | — | US | disclosed |
| US-4221729-A | HAIR DYES | L'OREAL (FR) | 1980-09-09 | — | — | US | disclosed |
| US-4184844-A | Storage stable indoaniline and indophenol dye solutions, a process for producing the same and hair dye compositions containing the same | L'OREAL (FR) | 1980-01-22 | — | — | US | disclosed |