Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11315137 | 0.88 | MTNR1B (0.39) | MAPTALDH1A1MAPK1HSD17B10LMNA | |
| SCHEMBL11308355 | 0.87 | MAPT (0.36) | MAPTALDH1A1MAPK1LMNAGAA | |
| SCHEMBL11309414 | 0.86 | MAPT (0.35) | MAPTALDH1A1LMNASMN1; SMN2GAA | |
| SCHEMBL10787625 | 0.85 | ALDH1A1 (0.36) | MAPTALDH1A1MAPK1GFERSMN1; SMN2 | |
| SCHEMBL11312372 | 0.80 | MAPT (0.34) | MAPTALDH1A1MAPK1HSD17B10LMNA | |
| SCHEMBL11306628 | 0.80 | KDM4E (0.37) | MAPTALDH1A1HSD17B10LMNASMN1; SMN2 | |
| SCHEMBL11330897 | 0.79 | PABPC1 (0.53) | MAPTALDH1A1MAPK1HSD17B10LMNA | |
| SCHEMBL10786288 | 0.79 | KDM4E (0.35) | MAPTALDH1A1LMNAGAAKDM4E | |
| SCHEMBL11318486 | 0.78 | KDM4E (0.35) | MAPTKDM4EHTT | |
| SCHEMBL13206444 | 0.75 | MAPT (0.36) | MAPTALDH1A1MAPK1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4221729-A | HAIR DYES | L'OREAL (FR) | 1980-09-09 | — | — | US | claimed |
| US-4248591-A | HAIR DYES | L'OREAL (FR) | 1981-02-03 | — | — | US | disclosed |
| US-4221729-A | HAIR DYES | L'OREAL (FR) | 1980-09-09 | — | — | US | disclosed |
| US-3977825-A | Indoanilines in keratinic fiber dye cmpositions | L'OREAL (FR) | 1976-08-31 | — | — | US | disclosed |